Package: cytometree Type: Package Title: Automated Cytometry Gating and Annotation Version: 2.0.6 Date: 2025-07-24 Authors@R: c(person(given = "Chariff", family = "Alkhassim", role = c("aut")), person(given = "Boris P", family = "Hejblum", email = "boris.hejblum@u-bordeaux.fr", role = c("cre", "aut")), person(given = "Anthony", family = "Devaux", role = c("aut")), person(given = "Van Hung Huynh", family = "Tran", role = c("aut")), person(given = "Melany", family = "Durand", role = c("aut")) ) Maintainer: Boris P Hejblum LinkingTo: Rcpp, RcppArmadillo Description: Given the hypothesis of a bi-modal distribution of cells for each marker, the algorithm constructs a binary tree, the nodes of which are subpopulations of cells. At each node, observed cells and markers are modeled by both a family of normal distributions and a family of bi-modal normal mixture distributions. Splitting is done according to a normalized difference of AIC between the two families. Method is detailed in: Commenges, Alkhassim, Gottardo, Hejblum & Thiebaut (2018) . License: LGPL-3 | file LICENSE LazyData: true Depends: R (>= 3.1.0), Rcpp (>= 0.12.11) Imports: ggplot2, graphics, igraph, mclust, methods, stats, cowplot, GoFKernel RoxygenNote: 7.3.2 URL: https://sistm.github.io/cytometree/, https://github.com/sistm/Cytometree/ BugReports: https://github.com/sistm/Cytometree/issues Encoding: UTF-8 Suggests: knitr, formatR, rmarkdown, viridis, testthat VignetteBuilder: knitr Config/pak/sysreqs: libglpk-dev libxml2-dev Repository: https://sistm.r-universe.dev Date/Publication: 2025-07-26 23:17:03 UTC RemoteUrl: https://github.com/sistm/cytometree RemoteRef: HEAD RemoteSha: 2280b5f2f5291dc5d9defb0605bb8c3066861120 NeedsCompilation: yes Packaged: 2026-07-03 22:54:57 UTC; root Author: Chariff Alkhassim [aut], Boris P Hejblum [cre, aut], Anthony Devaux [aut], Van Hung Huynh Tran [aut], Melany Durand [aut]